Department of Defense Prostate Cancer Research Programs FY11
The Fiscal Year 2011 (FY11) Defense Appropriations Act provides $ 80M to the Department of Defense (DOD) Prostate Cancer Research Program (PCRP) to fund research that will eliminate death and suffering from prostate cancer. This program is administered by the U.S. Army Medical Research and Materiel Command (USAMRMC) through the Office of the Congressionally Directed Medical Research Programs (CDMRP).
A summary of PCRP funding opportunities is provided below. Detailed descriptions of each of the funding opportunities, evaluation criteria, and submission requirements can be found in the FY11 PCRP Program Announcements. Each Program Announcement is available electronically for downloading from the Grants.gov website (http://www.grants.gov), the CDMRP website (http://cdmrp.army.mil/) and the CDMRP eReceipt System (https://cdmrp.org).
Brief descriptions of each of these award mechanisms are available on the Congressionally Directed Medical Research Programs website at http://cdmrp.army.mil/funding/pcrp.shtml
Submission Deadlines:
Award Mechanisms with Emphasis on Innovation:
Idea Development Award
http://www07.grants.gov/search/search.do?&mode=VIEW&flag2006=false&oppId=89273
Pre-Application (Pre-proposal): June 1, 2011
Application: August 23, 2011
Synergistic Idea Development Award
http://www07.grants.gov/search/search.do?&mode=VIEW&flag2006=false&oppId=89274
Pre-Application (Pre-proposal): June 1, 2011
Application: August 23, 2011
Award Mechanisms with Emphasis on Impact:
Clinical Trial Award
Maximum funding $ 375K in direct costs *Preproposal is required; application submission is by invitation only *Supports rapid execution of clinical trials to test interventions with the potential to have a major impact on the treatment or management of prostate cancer *Studies in a broad range of areas may be submitted *Investigational New Drug or Investigational Device Exemption approvals, if applicable must be in place before submission of the application *Sufficient study material must be available for the study at the time the award is made *PI must demonstrate availability and access to suitable human subject population that will support a meaningful outcome of the trial; population must be of sufficient size to clearly answer the objectives of the study *Clinical trials are expected to be initiated within 12 months of the award date.
Pre-application: June 10, 2011
Application: September 1, 2011
Impact Award
Maximum funding $ 750K in direct costs *Pre-propsoal is required; application submission is by invitation only *Supports high-impact studies towards reducing or eliminating the problem of overtreatment of primary prostate cancer *Multidisciplinary teams inclusive of clinical specialists are a key feature *Preliminary data to support feasibility are required.
Pre-Application: June 10, 2011
Application: September 1, 2011
Laboratory-Clinical Transition Award
Maximum funding $ 750K in direct costs *Preproposal is required; application submission is by invitation only *Supports product-driven preclinical studies of promising lead agents that have the potential to revolutionize prostate cancer clinical care *PIs are expected to demonstrate within the application (1) a validated target, (2) access to either one lead agent or a limited number of lead agents for optimization, and (3) the agent's mechanism of action *Preliminary data are required to demonstrate validated target availability and distribution in relevant human tissues and substantive information from model systems that supports potential efficacy of the lead agent(s) in humans *Does not support target discovery, drug screening, device development, development of diagnostic biomarkers, studies of new combinations of conventional therapeutics in clinical testing or practice, or clinical trials *Supports research that ranges from preclinical study of the lead agent(s) through its cGMP production.
Pre-Application: June 10, 2011
Application: September 1, 2011
A pre-application will be required and must be submitted through the CDMRP eReceipt website (http://cdmrp.org) prior to the pre-application deadline. Applications must be submitted through the federal government's single-entry portal, Grants.gov. Requests for email notification of the program announcements release may be sent to help@cdmrp.org. For more information about the PCRP or other CDMRP-administered programs, please visit the CDMRP website (http://cdmrp.army.mil).
Points of Contact:
CDMRP Public Affairs
301-619-9783
CDMRP.PublicAffairs@amedd.army.mil
